Detection of septic transfusion reactions to platelet transfusions by active and passive surveillance

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Detection of septic transfusion reactions to platelet transfusions by active and passive surveillance.

Septic transfusion reactions (STRs) resulting from transfusion of bacterially contaminated platelets are a major hazard of platelet transfusion despite recent interventions. Active and passive surveillance for bacterially contaminated platelets was performed over 7 years (2007-2013) by culture of platelet aliquots at time of transfusion and review of reported transfusion reactions. All platelet...

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Regular Article TRANSFUSION MEDICINE Detection of septic transfusion reactions to platelet transfusions by active and passive surveillance

• Bacterial sepsis from contaminated platelet transfusions continues to occur despite recent interventions; additional measures are needed. • STR to platelet transfusion is frequently not recognized or reported; use of recent AABB criteria showed highest diagnostic sensitivity. Septic transfusion reactions (STRs) resulting from transfusion of bacterially contaminated platelets are a major hazar...

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Platelet Septic Transfusion Reactions in Patients With Hemato-Oncological Diseases

Background & Objective: Bacterial, contamination of blood components are a significant risk for transfusion reactions. Inherently, platelet concentrates (PCs) are vulnerable to bacterial contamination, due to the storage condition of processed PCs at room temperature, which provide very suitable conditions for the proliferation of microorganisms....

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Transfusion Medicine 2 Platelet transfusions

Ever since platelet transfusions were shown to reduce mortality from haemorrhage in patients with acute leukaemia in the 1950s, the use of this therapy has steadily grown to become an essential part of the treatment of cancer, haematological malignancies, marrow failure, and haematopoietic stem cell transplantation. Today, more than 1·5 million platelet products are transfused in the USA each y...

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ABC of Transfusion. Platelet and granulocyte transfusions.

Multiple.packs for collection of blood. Left to right: transfer pack containing optimal additive solution; primary pack containing 450 ml of blood in anticoagulant; and pack for collection of platelets with extended shelf ife. Transfusion of platelets and granulocytes may be needed for patients with life threatening thrombocytopenia and neutropenia caused by bone marrow failure. These may be th...

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ژورنال

عنوان ژورنال: Blood

سال: 2016

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood-2015-07-655944